Please use this identifier to cite or link to this item: https://doi.org/10.1093/rheumatology/keq428
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dc.titleRetinal vascular calibre is altered in patients with rheumatoid arthritis: A biomarker of disease activity and cardiovascular risk?
dc.contributor.authorvan Doornum, S.
dc.contributor.authorStrickl, G.
dc.contributor.authorKawasaki, R.
dc.contributor.authorXie, J.
dc.contributor.authorWicks, I.P.
dc.contributor.authorHodgson, L.A.B.
dc.contributor.authorWong, T.Y.
dc.date.accessioned2014-11-26T07:47:53Z
dc.date.available2014-11-26T07:47:53Z
dc.date.issued2011-05
dc.identifier.citationvan Doornum, S., Strickl, G., Kawasaki, R., Xie, J., Wicks, I.P., Hodgson, L.A.B., Wong, T.Y. (2011-05). Retinal vascular calibre is altered in patients with rheumatoid arthritis: A biomarker of disease activity and cardiovascular risk?. Rheumatology 50 (5) : 939-943. ScholarBank@NUS Repository. https://doi.org/10.1093/rheumatology/keq428
dc.identifier.issn14620324
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109607
dc.description.abstractObjectives: Alterations in retinal vascular calibre, particularly wider venular calibre, have been independently associated with elevated markers of inflammation and cardiovascular risk in the general population. We hypothesized that retinal vascular calibre would be altered in patients with RA, who are known to have both elevated cardiovascular risk and chronic, systemic inflammation. Methods: Retinal vascular calibre was measured from digital retinal photographs using computerized methods in 51 RA patients and 51 age- and gender-matched controls. Retinal vascular calibre was compared between RA and control patients with adjustment for relevant variables including cardiovascular risk factors and companion vessel calibre. The relationship between retinal venular calibre and inflammation was assessed by comparing controls and RA patients with high and lower disease activity. Results: Retinal venular calibre [mean (S.D.)] was significantly wider in RA patients than in controls [235.9 (24.6) vs 211.6 (21.0) μm, P
dc.sourceScopus
dc.subjectAtherosclerosis
dc.subjectCardiovascular
dc.subjectInflammation
dc.subjectOcular photography
dc.subjectRetinal vascular calibre
dc.subjectRheumatoid arthritis
dc.subjectRisk
dc.subjectVascular
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1093/rheumatology/keq428
dc.description.sourcetitleRheumatology
dc.description.volume50
dc.description.issue5
dc.description.page939-943
dc.description.codenRUMAF
dc.identifier.isiut000289840300019
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