Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ajo.2006.07.040
DC FieldValue
dc.titleIs Early Age-related Macular Degeneration Associated With Cerebral MRI Changes? The Atherosclerosis Risk in Communities Study
dc.contributor.authorGrosso, A.
dc.contributor.authorMosley, T.H.
dc.contributor.authorKlein, R.
dc.contributor.authorCouper, D.J.
dc.contributor.authorTikellis, G.
dc.contributor.authorWong, T.Y.
dc.date.accessioned2014-11-26T07:45:41Z
dc.date.available2014-11-26T07:45:41Z
dc.date.issued2007-01
dc.identifier.citationGrosso, A., Mosley, T.H., Klein, R., Couper, D.J., Tikellis, G., Wong, T.Y. (2007-01). Is Early Age-related Macular Degeneration Associated With Cerebral MRI Changes? The Atherosclerosis Risk in Communities Study. American Journal of Ophthalmology 143 (1) : 157-159. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ajo.2006.07.040
dc.identifier.issn00029394
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109425
dc.description.abstractPurpose: To examine the relation of early age-related macular degeneration (AMD) with cerebral magnetic resonance imaging (MRI) changes. Design: Population-based, cross-sectional study. Methods: A sample of 1,684 persons ages 51 to 72 years with no history of stroke had cerebral MRI and retinal photography. MRI scans were graded for severity of white matter lesions (WML), sulcal widening (SW), and ventricular enlargement (VE). AMD was graded from retinal photographs. Results: After adjustment for age, gender, race, or center, early AMD (5.0% of participants) was not significantly associated with WML (odds ratio [OR] 1.0, 95% confidence intervals [CI], 0.6 to 1.6), SW (OR 0.6, 95% CI, 0.4 to 1.2), or VE (OR 1.0, 95% CI, 0.6 to 1.8). Conclusions: These data showed no statistically significant association of early AMD with cerebral MRI changes, but the study was limited by a small number of cases with wide CIs. Further studies may clarify these associations. © 2007 Elsevier Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ajo.2006.07.040
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.ajo.2006.07.040
dc.description.sourcetitleAmerican Journal of Ophthalmology
dc.description.volume143
dc.description.issue1
dc.description.page157-159
dc.description.codenAJOPA
dc.identifier.isiut000243311700027
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.