Please use this identifier to cite or link to this item:
https://doi.org/10.1038/cmi.2008.2
DC Field | Value | |
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dc.title | The classical and regulatory functions of C1q in immunity and autoimmunity | |
dc.contributor.author | Lu, J. | |
dc.contributor.author | Teh, B.K. | |
dc.contributor.author | Wang, L. | |
dc.contributor.author | Wang, Y. | |
dc.contributor.author | Tan, Y.S. | |
dc.contributor.author | Lai, M.C. | |
dc.contributor.author | Reid, K.B.M. | |
dc.date.accessioned | 2014-11-25T09:49:06Z | |
dc.date.available | 2014-11-25T09:49:06Z | |
dc.date.issued | 2008-02 | |
dc.identifier.citation | Lu, J., Teh, B.K., Wang, L., Wang, Y., Tan, Y.S., Lai, M.C., Reid, K.B.M. (2008-02). The classical and regulatory functions of C1q in immunity and autoimmunity. Cellular and Molecular Immunology 5 (1) : 9-21. ScholarBank@NUS Repository. https://doi.org/10.1038/cmi.2008.2 | |
dc.identifier.issn | 16727681 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/108692 | |
dc.description.abstract | A classical function of C1q is to bind immune complexes and initiate complement activation producing membrane lytic complexes, opsonins and anaphylatoxins. This classical pathway of complement activation is also elicited when C1q binds some other ligands. Besides complement activation, C1q also regulates cell differentiation, adhesion, migration, activation and survival. C1q deficiency is associated with autoimmunity as well as increased susceptibility to infections. In this article, we discuss the basic properties of C1q, its expression, and classical and regulatory functions. © 2008 by The Chinese Society of Immunology. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1038/cmi.2008.2 | |
dc.source | Scopus | |
dc.subject | apoptotic cell | |
dc.subject | autoimmunity | |
dc.subject | C1q | |
dc.subject | dendritic cell | |
dc.subject | macrophage | |
dc.type | Review | |
dc.contributor.department | MICROBIOLOGY | |
dc.description.doi | 10.1038/cmi.2008.2 | |
dc.description.sourcetitle | Cellular and Molecular Immunology | |
dc.description.volume | 5 | |
dc.description.issue | 1 | |
dc.description.page | 9-21 | |
dc.identifier.isiut | 000254276400002 | |
Appears in Collections: | Staff Publications |
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