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Title: Acute symptomatic seizures and hippocampus damage: DWI and MRS findings
Authors: Parmar, H.
Lim, S.-H.
Tan, N.C.K.
Lim, C.C.T. 
Issue Date: Jun-2006
Citation: Parmar, H., Lim, S.-H., Tan, N.C.K., Lim, C.C.T. (2006-06). Acute symptomatic seizures and hippocampus damage: DWI and MRS findings. Neurology 66 (11) : 1732-1735. ScholarBank@NUS Repository.
Abstract: The authors describe diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) changes in the hippocampus within 48 hours of acute symptomatic seizures or status epilepticus in 12 patients. DWI showed increased signal and a decreased apparent diffusion coefficient (ADC) in all patients, with corresponding lactate detected on MRS in six patients and EEG seizure activity in nine patients. On follow-up, the atrophic hippocampus had an increased ADC in six patients. DWI and MRS may predict development of hippocampal sclerosis. Copyright © 2006 by AAN Enterprises, Inc.
Source Title: Neurology
ISSN: 00283878
DOI: 10.1212/01.wnl.0000218207.18707.f4
Appears in Collections:Staff Publications

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