Please use this identifier to cite or link to this item: https://doi.org/10.1093/bioinformatics/btr007
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dc.titleA method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies
dc.contributor.authorOng, R.T.-H.
dc.contributor.authorLiu, X.
dc.contributor.authorPoh, W.-T.
dc.contributor.authorSim, X.
dc.contributor.authorChia, K.-S.
dc.contributor.authorTeo, Y.-Y.
dc.date.accessioned2014-11-25T09:43:33Z
dc.date.available2014-11-25T09:43:33Z
dc.date.issued2011-03
dc.identifier.citationOng, R.T.-H., Liu, X., Poh, W.-T., Sim, X., Chia, K.-S., Teo, Y.-Y. (2011-03). A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies. Bioinformatics 27 (6) : 822-828. ScholarBank@NUS Repository. https://doi.org/10.1093/bioinformatics/btr007
dc.identifier.issn13674803
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/108233
dc.description.abstractMotivation: Methods for detecting positive selection relied on finding evidence of long haplotypes to identify candidate regions under selection. However, these methods generally do not identify the length and form of the selected haplotype. Results: We present HapFinder, a method which can find the common longest haplotype under three different settings from a database, which is relevant in the analysis of positive selection in population genetics and also in medical genetics for finding the likely haplotype form carrying the causal allele at the functional polymorphism. © The Author 2011. Published by Oxford University Press. All rights reserved.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.contributor.departmentLIFE SCIENCES INSTITUTE
dc.contributor.departmentGENOME INSTITUTE OF SINGAPORE
dc.contributor.departmentSTATISTICS & APPLIED PROBABILITY
dc.description.doi10.1093/bioinformatics/btr007
dc.description.sourcetitleBioinformatics
dc.description.volume27
dc.description.issue6
dc.description.page822-828
dc.description.codenBOINF
dc.identifier.isiut000288277300012
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