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Title: Disordered water homeostasis in Asian patients with schizophrenia
Authors: Chong, S.-A.
Tan, L.-L.
Wong, M.-C.
Woo, S.-C.
Tan, C.-H. 
Ng, L.-L.
Keywords: Asian
Issue Date: Dec-1997
Citation: Chong, S.-A.,Tan, L.-L.,Wong, M.-C.,Woo, S.-C.,Tan, C.-H.,Ng, L.-L. (1997-12). Disordered water homeostasis in Asian patients with schizophrenia. Australian and New Zealand Journal of Psychiatry 31 (6) : 869-873. ScholarBank@NUS Repository.
Abstract: Objective: The aim of this study was to determine the prevalence of polydipsia-hyponatremia among patients with schizophrenia in an Asian mental hospital. Method: Seven hundred and twenty-eight inpatients with schizophrenia were assessed for polydipsia-hyponatremia using case notes reviews, specific gravity of urine, normalised diurnal weight gain, and serum sodium levels. Results: One hundred and three (13.8%) patients had polydipsia, 30 (4.1%) had polydipsia-hyponatremia and 14 (1.9%) had a history of water intoxication. Eight of the 30 patients were receiving carbamazepine, three were on tricyclic antidepressants and two had diabetes mellitus and were on sulfonylureas. Conclusion: The prevalence of water intoxication among polydipsic patients was low compared to Western studies. This could be due to different methods of assessing polyuria, or ethnic differences and/or the prohibition of smoking in our patients. Certain medications might have also contributed to hyponatremia.
Source Title: Australian and New Zealand Journal of Psychiatry
ISSN: 00048674
Appears in Collections:Staff Publications

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