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Title: The changing field of vaccine development in the genomics era
Authors: Brusic, V. 
August, J.T. 
Keywords: Immune system diversity
Pathogen diversity
Spectral responses
Vaccine informatics
Issue Date: Sep-2004
Citation: Brusic, V., August, J.T. (2004-09). The changing field of vaccine development in the genomics era. Pharmacogenomics 5 (6) : 597-600. ScholarBank@NUS Repository.
Abstract: An improved understanding of the human immune system and the genetic make-up of pathogens, together with advances in instrumentation and bioinformatics, have provided new insights into the variation of immune responses to vaccines within the human population. Pathogen variation and the diversity of the immune system components within the human population make the design of universal vaccines difficult. New subunit vaccines that target immunologically similar subgroups of the human population and representative pathogen variants are emerging from research that combines immunomics, pathogen genomics, and high-throughput instrumentation. 2004 © Future Medicine Ltd.
Source Title: Pharmacogenomics
ISSN: 14622416
DOI: 10.1517/14622416.5.6.597
Appears in Collections:Staff Publications

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