Syndecan-2 and decorin: Proteoglycans with a difference-implications in keloid pathogenesis

Please use this identifier to cite or link to this item: https://doi.org/10.1097/TA.0b013e3181c4070d

Title:	Syndecan-2 and decorin: Proteoglycans with a difference-implications in keloid pathogenesis
Authors:	Mukhopadhyay, A. Wong, M.Y. Chan, S.Y. Do, D.V. Khoo, A. Ong, C.T. Cheong, H.H. Lim, I.J. Phan, T.T.
Keywords:	Decorin Epithelial-mesenchymal interactions FGF-2 Fibroblasts Keloid Scar Keratinocytes Syndecan-2 TGF-β
Issue Date:	Apr-2010
Citation:	Mukhopadhyay, A., Wong, M.Y., Chan, S.Y., Do, D.V., Khoo, A., Ong, C.T., Cheong, H.H., Lim, I.J., Phan, T.T. (2010-04). Syndecan-2 and decorin: Proteoglycans with a difference-implications in keloid pathogenesis. Journal of Trauma - Injury, Infection and Critical Care 68 (4) : 999-1008. ScholarBank@NUS Repository. https://doi.org/10.1097/TA.0b013e3181c4070d
Abstract:	BACKGROUND: Growth factors and cytokines involved in the wound healing process seem to be immobilized at the cell surface and extracellular matrix via binding with proteoglycans, making them important modulators of cell dynamics. Our aim was to investigate the expression of two proteoglycans, namely syndecan-2 and decorin, and to elucidate their role in the pathogenesis of an aberrant wound healing process leading to keloid scar. METHODS
Source Title:	Journal of Trauma - Injury, Infection and Critical Care
URI:	http://scholarbank.nus.edu.sg/handle/10635/106385
ISSN:	00225282
DOI:	10.1097/TA.0b013e3181c4070d
Appears in Collections:	Staff Publications

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