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Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/106223
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dc.titlePlasmepsin II inhibitory activity of alkoxylated and hydroxylated chalcones
dc.contributor.authorSriwilaijaroen, N.
dc.contributor.authorLiu, M.
dc.contributor.authorGo, M.-L.
dc.contributor.authorWilairat, P.
dc.date.accessioned2014-10-29T01:56:59Z
dc.date.available2014-10-29T01:56:59Z
dc.date.issued2006-07
dc.identifier.citationSriwilaijaroen, N.,Liu, M.,Go, M.-L.,Wilairat, P. (2006-07). Plasmepsin II inhibitory activity of alkoxylated and hydroxylated chalcones. Southeast Asian Journal of Tropical Medicine and Public Health 37 (4) : 607-612. ScholarBank@NUS Repository.
dc.identifier.issn01251562
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/106223
dc.description.abstractSixteen antimalarial alkoxylated and hydroxylated chalcones were tested for their ability to inhibit recombinant plasmepsin II in vitro. The best inhibitory compounds had either a chloro or dimethylamino group at the 4-position of phenyl ring A in the chalcone template. Combination of the chalcones with chloroquine showed additivity or mild antagonism of Plasmodium falciparum K1 growth in culture.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPHARMACY
dc.description.sourcetitleSoutheast Asian Journal of Tropical Medicine and Public Health
dc.description.volume37
dc.description.issue4
dc.description.page607-612
dc.identifier.isiutNOT_IN_WOS
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