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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.jinorgbio.2007.01.010
DC FieldValue
dc.titleCytotoxicity, qualitative structure-activity relationship (QSAR), and anti-tumor activity of bismuth dithiocarbamate complexes
dc.contributor.authorLi, H.
dc.contributor.authorLai, C.S.
dc.contributor.authorWu, J.
dc.contributor.authorHo, P.C.
dc.contributor.authorde Vos, D.
dc.contributor.authorTiekink, E.R.T.
dc.date.accessioned2014-10-29T01:50:45Z
dc.date.available2014-10-29T01:50:45Z
dc.date.issued2007-05
dc.identifier.citationLi, H., Lai, C.S., Wu, J., Ho, P.C., de Vos, D., Tiekink, E.R.T. (2007-05). Cytotoxicity, qualitative structure-activity relationship (QSAR), and anti-tumor activity of bismuth dithiocarbamate complexes. Journal of Inorganic Biochemistry 101 (5) : 809-816. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jinorgbio.2007.01.010
dc.identifier.issn01620134
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/105791
dc.description.abstractBismuth dithiocarbamate complexes of general formula Bi(S2CNR2)3 demonstrate potent in vitro cytotoxicity against a panel of seven human cancer cell lines; a structure-activity relationship has been established. Potency exhibited by the R = Et (2) derivative, for example, is unrivalled by standard cancer drugs with the exception of paclitaxel. In vivo studies indicate a significant anti-tumor effect exerted by (2) against both OVCAR-3, an ovarian cancer cell line, and HT-29, a colon carcinoma cell line. © 2007 Elsevier Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.jinorgbio.2007.01.010
dc.sourceScopus
dc.subjectAnti-tumor
dc.subjectBismuth complexes
dc.subjectCytotoxicity
dc.subjectDithiocarbamate complexes
dc.typeArticle
dc.contributor.departmentPHARMACY
dc.description.doi10.1016/j.jinorgbio.2007.01.010
dc.description.sourcetitleJournal of Inorganic Biochemistry
dc.description.volume101
dc.description.issue5
dc.description.page809-816
dc.description.codenJIBID
dc.identifier.isiut000246639700009
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