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Title: Concise, efficient and practical assembly of bromo-5,6-dimethoxyindole building blocks
Authors: Huleatt, P.B.
Lau, J.
Chua, S.
Tan, Y.L.
Duong, H.A.
Chai, C.L.L. 
Keywords: Indoles
Issue Date: 23-Mar-2011
Citation: Huleatt, P.B., Lau, J., Chua, S., Tan, Y.L., Duong, H.A., Chai, C.L.L. (2011-03-23). Concise, efficient and practical assembly of bromo-5,6-dimethoxyindole building blocks. Tetrahedron Letters 52 (12) : 1339-1342. ScholarBank@NUS Repository.
Abstract: A concise, efficient and simple route to a series of bromoindole building blocks is described. The synthetic routes are highlighted by purification-free preparation of o-nitrocinnamate intermediates and clean, modified Cadogan indole syntheses. The scope of this indole synthesis has been explored and expanded through the use of a range of solvents and easily removable phosphine reagents. © 2011 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
ISSN: 00404039
DOI: 10.1016/j.tetlet.2011.01.076
Appears in Collections:Staff Publications

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