Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/105726
DC FieldValue
dc.titleChitosan microspheres prepared by emulsification and ionotropic gelation
dc.contributor.authorLim, L.Y.
dc.contributor.authorWan, L.S.C.
dc.contributor.authorThai, P.Y.
dc.date.accessioned2014-10-29T01:49:39Z
dc.date.available2014-10-29T01:49:39Z
dc.date.issued1997
dc.identifier.citationLim, L.Y.,Wan, L.S.C.,Thai, P.Y. (1997). Chitosan microspheres prepared by emulsification and ionotropic gelation. Drug Development and Industrial Pharmacy 23 (10) : 981-985. ScholarBank@NUS Repository.
dc.identifier.issn03639045
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/105726
dc.description.abstractAn attempt was made to prepare chitosan microspheres by an emulsion-phase separation technique but without the usual use of glutaraldehyde as a cross-linking agent. Instead, ionotropic gelation was employed in a w/o emulsion. The effect of formation factors was examined. The results showed that microspheres so formed were spherical, free-flowing, and had smooth surfaces. The rate of addition of counterions was important. Gelation of chitosan droplets should take place before the destabilizing effect of the counterions occurred. This effect is associated with the increase in aqueous phase volume when the counterion solution is incorporated.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPHARMACY
dc.description.sourcetitleDrug Development and Industrial Pharmacy
dc.description.volume23
dc.description.issue10
dc.description.page981-985
dc.description.codenDDIPD
dc.identifier.isiutNOT_IN_WOS
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