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Title: A synthesis of a novel heterocyclic system: 2H-furo[3,2-b][1,4] benzothiazin-2-one
Authors: Dolzhenko, A.V. 
Chui, W.-K. 
Issue Date: 1-Nov-2004
Citation: Dolzhenko, A.V.,Chui, W.-K. (2004-11-01). A synthesis of a novel heterocyclic system: 2H-furo[3,2-b][1,4] benzothiazin-2-one. Heterocycles 63 (11) : 2623-2626. ScholarBank@NUS Repository.
Abstract: A synthesis of 3-methyl-2H-furo[3,2-b][1,4]benzothiazin-2-ones (10a,b) is described. o-Aminothiophenols (1a,b) undergo condensation with citraconic anhydride followed by cyclization and oxidation of the resulting 2-(3,4-dihydro-2H-1,4-benzothiazin-2-yl)propanoic acids (5) with thionyl chloride gives moderate yield of 10a,b.
Source Title: Heterocycles
ISSN: 03855414
Appears in Collections:Staff Publications

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