Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.gene.2013.08.014
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dc.titleAssociation of Interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore
dc.contributor.authorAndiappan, A.K.
dc.contributor.authorRotzschke, O.
dc.contributor.authorWang, D.Y.
dc.contributor.authorChew, F.T.
dc.date.accessioned2014-10-27T08:46:28Z
dc.date.available2014-10-27T08:46:28Z
dc.date.issued2013-10-25
dc.identifier.citationAndiappan, A.K., Rotzschke, O., Wang, D.Y., Chew, F.T. (2013-10-25). Association of Interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore. Gene 529 (2) : 357-358. ScholarBank@NUS Repository. https://doi.org/10.1016/j.gene.2013.08.014
dc.identifier.issn03781119
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/102278
dc.description.abstractIn this study, we report our findings as we evaluated the association of IL-13 SNP rs20541 to AR as reported in the meta-analysis (Ying, X-J et al., April, Gene 2013) in an Asian population of 1322 ethnic Chinese recruited in Singapore well defined and characterized for allergic rhinitis. The SNP was significantly associated with AR at an odds ratio of 1.57 for the homozygous genotype comparisons indicating a strong risk for AR. This highlights the importance of this mutation in Asian populations for risk towards allergic phenotypes and also warrants further functional work to characterize the mechanism behind this genetic predisposition. © 2013.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.gene.2013.08.014
dc.sourceScopus
dc.subjectAR
dc.subjectGenetics
dc.subjectIL-13
dc.subjectRs20541
dc.subjectSingapore Chinese
dc.typeOthers
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1016/j.gene.2013.08.014
dc.description.sourcetitleGene
dc.description.volume529
dc.description.issue2
dc.description.page357-358
dc.description.codenGENED
dc.identifier.isiut000325122800025
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