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https://doi.org/10.1016/j.fertnstert.2005.11.042
| Title: | The search for factors in human feeders that support the derivation and propagation of human embryonic stem cells: preliminary studies using transcriptome profiling by serial analysis of gene expression | Authors: | Kueh, J. Richards, M. Ng, S.-W. Chan, W.-K. Bongso, A. |
Issue Date: | Jun-2006 | Citation: | Kueh, J., Richards, M., Ng, S.-W., Chan, W.-K., Bongso, A. (2006-06). The search for factors in human feeders that support the derivation and propagation of human embryonic stem cells: preliminary studies using transcriptome profiling by serial analysis of gene expression. Fertility and Sterility 85 (6) : 1843-1846. ScholarBank@NUS Repository. https://doi.org/10.1016/j.fertnstert.2005.11.042 | Abstract: | Serial analysis of gene expression (SAGE) was used to obtain the transcriptome profiles of a supportive human fetal skin feeder (Detroit 551) and a nonsupportive human fetal lung feeder (MRC-5) for human embryonic stem cells. A pairwise comparison of the two SAGE profiles showed that fibroblast growth factor-2 (FGF2), a bone morphogenetic protein 4 pathway inhibitor, Gremlin 1, and several extracellular matrix proteins that could potentially aid human embryonic stem cell attachment and growth were highly expressed in Detroit 551 fibroblasts. © 2006 American Society for Reproductive Medicine. | Source Title: | Fertility and Sterility | URI: | http://scholarbank.nus.edu.sg/handle/10635/102006 | ISSN: | 00150282 | DOI: | 10.1016/j.fertnstert.2005.11.042 |
| Appears in Collections: | Staff Publications |
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