Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1365-313X.2008.03709.x
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dc.titleRepression of the floral transition via histone H2B monoubiquitination
dc.contributor.authorGu, X.
dc.contributor.authorJiang, D.
dc.contributor.authorWang, Y.
dc.contributor.authorBachmair, A.
dc.contributor.authorHe, Y.
dc.date.accessioned2014-10-27T08:38:35Z
dc.date.available2014-10-27T08:38:35Z
dc.date.issued2009-02
dc.identifier.citationGu, X., Jiang, D., Wang, Y., Bachmair, A., He, Y. (2009-02). Repression of the floral transition via histone H2B monoubiquitination. Plant Journal 57 (3) : 522-533. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1365-313X.2008.03709.x
dc.identifier.issn09607412
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/101566
dc.description.abstractThe Rad6-Bre1 complex monoubiquitinates histone H2B in target gene chromatin, and plays an important role in positively regulating gene expression in yeast. Here, we show that the Arabidopsis relatives of the yeast Rad6, ubiquitin-conjugating enzyme 1 (UBC1) and UBC2, redundantly mediate histone H2B monoubiquitination, and upregulate the expression of FLOWERING LOCUS C (FLC; a central flowering repressor in Arabidopsis) and FLC relatives, and also redundantly repress flowering, the developmental transition from a vegetative to a reproductive phase that is critical in the plant life cycle. Moreover, we have found that Arabidopsis relatives of the yeast Bre1, including HISTONE MONOUBIQUITINATION 1 (HUB1) and HUB2, also upregulate the expression of FLC and FLC relatives, and that HUB1 genetically interacts with UBC1 and UBC2 to repress the floral transition. These findings are consistent with a model in which HUB1 and HUB2 specifically interact with and direct UBC1 and UBC2 to monoubiquitinate H2B in developmental genes, and thus regulate developmental processes in plants. © 2008 The Authors.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1111/j.1365-313X.2008.03709.x
dc.sourceScopus
dc.subjectFLC
dc.subjectFLC relatives
dc.subjectFlowering
dc.subjectH2B monoubiquitination
dc.subjectUbiquitin-conjugating enzyme
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1111/j.1365-313X.2008.03709.x
dc.description.sourcetitlePlant Journal
dc.description.volume57
dc.description.issue3
dc.description.page522-533
dc.description.codenPLJUE
dc.identifier.isiut000262695800012
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