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Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/101079
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dc.titleMembrane destabilization by monomeric hIAPP observed by imaging fluorescence correlation spectroscopy
dc.contributor.authorBag, N.
dc.contributor.authorAli, A.
dc.contributor.authorChauhan, V.S.
dc.contributor.authorWohland, T.
dc.contributor.authorMishra, A.
dc.date.accessioned2014-10-27T08:33:18Z
dc.date.available2014-10-27T08:33:18Z
dc.date.issued2013-10-14
dc.identifier.citationBag, N., Ali, A., Chauhan, V.S., Wohland, T., Mishra, A. (2013-10-14). Membrane destabilization by monomeric hIAPP observed by imaging fluorescence correlation spectroscopy. Chemical Communications 49 (80) : 9155-9157. ScholarBank@NUS Repository.
dc.identifier.issn13597345
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/101079
dc.description.abstractMonomeric hIAPP significantly destabilizes both model and live cell membranes by increasing membrane fluidity. This interaction with membranes happens via carpet formation followed by lipid extraction in a concentration dependent manner and thus we propose that hIAPP aggregation prior to membrane interaction may not be necessary for its cytotoxicity. © 2013 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c3cc44880k
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.sourcetitleChemical Communications
dc.description.volume49
dc.description.issue80
dc.description.page9155-9157
dc.description.codenCHCOF
dc.identifier.isiut000324490200025
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