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Title: Developmental expression of a novel Ftz-F1 homologue, ff1b (NR5A4), in the zebrafish Danio rerio
Authors: Chai, C.
Chan, W.-K. 
Keywords: Danio rerio
One-eyed pinhead
Rostral diencephalon
Issue Date: 1-Mar-2000
Citation: Chai, C., Chan, W.-K. (2000-03-01). Developmental expression of a novel Ftz-F1 homologue, ff1b (NR5A4), in the zebrafish Danio rerio. Mechanisms of Development 91 (1-2) : 421-426. ScholarBank@NUS Repository.
Abstract: The Ftz-F1 genes encode orphan receptors of the nuclear receptor superfamily. The mammalian Ftz-F1 homologue, SF-1, has been found to be essential for the proper development of the adrenal-gonadal axis and it also plays a critical role in mammalian sex-determination. We report here the isolation and characterisation of a novel zebrafish Ftz-F1 gene, ff1b. Whole- mount in situ hybridization revealed onset of expression in the developing rostral diencephalon at 22 h post-fertilization (h.p.f.). Later, at 30 h.p.f., transcripts could be detected in the anterior regions of the pancreatic anlagen. Expression in both locations peaks at 36 h.p.f. and disappears at around 48 h.p.f. (C) 2000 Elsevier Science Ireland Ltd.
Source Title: Mechanisms of Development
ISSN: 09254773
DOI: 10.1016/S0925-4773(99)00312-3
Appears in Collections:Staff Publications

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