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Title: Application of advanced technologies in ageing research
Authors: Lim, C.-A.
Ng, H.-H. 
Issue Date: Jan-2007
Citation: Lim, C.-A., Ng, H.-H. (2007-01). Application of advanced technologies in ageing research. Mechanisms of Ageing and Development 128 (1) : 149-160. ScholarBank@NUS Repository.
Abstract: Several technologies that emerged in the post-genomic era have been particularly useful in dissecting the molecular mechanisms of complex biological processes through the systems approach. Here, we review how three of these technologies, namely transcriptional profiling, large-scale RNA interference (RNAi) and genome-wide location analysis of protein-DNA interactions, have been used in the study of ageing in metazoans. We also highlight recent developments of these three technologies and how these developments are applicable to ageing research. © 2006 Elsevier Ireland Ltd. All rights reserved.
Source Title: Mechanisms of Ageing and Development
ISSN: 00476374
DOI: 10.1016/j.mad.2006.11.024
Appears in Collections:Staff Publications

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