Please use this identifier to cite or link to this item:
|Title:||An Agrobacterium catalase is a virulence factor involved in tumorigenesis||Authors:||Xu, X.Q.
|Issue Date:||2000||Citation:||Xu, X.Q., Pan, S.Q. (2000). An Agrobacterium catalase is a virulence factor involved in tumorigenesis. Molecular Microbiology 35 (2) : 407-414. ScholarBank@NUS Repository. https://doi.org/10.1046/j.1365-2958.2000.01709.x||Abstract:||Most plant pathogenic bacteria adopt the type III secretion systems to secrete virulence factors and/or avirulence gene products, which trigger the plant hypersensitive response (HR) and the oxidative burst with hydrogen peroxide (H2O2) as the main component. However, the soil-borne plant pathogen Agrobacterium tumefaciens uses the type IV secretion pathway to deliver its oncogenic T-DNA that causes crown gall tumours on many plant species. A. tumefaciens does not elicit a typical HR on those plants. Here, we report that inactivation of one of A. tumefaciens catalases (which converts H2O2 to H2O and O2) by a transposon insertion highly attenuated the bacterial ability to cause tumours on plants and to tolerate H2O2 toxicity, but not the bacterial viability in the absence of exogenous H2O2. This provides the first genetic evidence that the Agrobacterium-plant interaction involves a plant defence response, such as H2O2 production, and that catalase is a virulence factor for a plant pathogen.||Source Title:||Molecular Microbiology||URI:||http://scholarbank.nus.edu.sg/handle/10635/100051||ISSN:||0950382X||DOI:||10.1046/j.1365-2958.2000.01709.x|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 4, 2020
WEB OF SCIENCETM
checked on May 26, 2020
checked on May 30, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.