Full Name
Sir David Lane
Main Affiliation
 
 
Email
mdcsdl@nus.edu.sg
 

Publications

Refined By:
Subject:  genetics
Subject:  Humans

Results 1-10 of 10 (Search time: 0.012 seconds).

Issue DateTitleAuthor(s)
12018Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenibLadds M.J.G.W.; Pastor-Fernández A.; Popova G.; van Leeuwen I.M.M.; Eng K.E.; Drummond C.J.; Johansson L.; Svensson R.; Westwood N.J.; McCarthy A.R.; Tholander F.; Popa M.; Lane D.P. ; McCormack E.; McInerney G.M.; Bhatia R.; Laín S.
22016Avoiding drug resistance through extended drug target interfaces: A case for stapled peptidesWei, S.J; Chee, S; Yurlova, L; Lane, D ; Verma, C ; Brown, C; Ghadessy, F
32017Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulationsYadahalli, S; Li, J ; Lane, D.P ; Gosavi, S; Verma, C.S 
42017Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based deliveryThean, D; Ebo, J.S; Luxton, T; Lee, X.C; Yuen, T.Y; Ferrer, F.J; Johannes, C.W; Lane, D.P ; Brown, C.J
52010Evaluation of an Actinomycin D/VX-680 aurora kinase inhibitor combination in p53-based cyclotherapy.Rao, B; van Leeuwen, I.M.; Higgins, M.; Campbel, J.; Thompson, A.M.; Lane, D.P. ; Lain, S.
62014High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemiaTan, B.X; Khoo, K.H; Lim, T.M ; Lane, D.P 
72008MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphismPaulin, F.E.M; O'Neill, M; McGregor, G; Cassidy, A; Ashfield, A; Ali, C.W; Munro, A.J; Baker, L; Purdie, C.A; Lane, D.P ; Thompson, A.M
82011Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretomeNeilsen, P.M; Noll, J.E; Suetani, R.J; Schulz, R.B; Al-Ejeh, F; Evdokiou, A; Lane, D.P ; Callen, D.F
92011P53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patientsBourdon, J.-C; Khoury, M.P; Diot, A; Baker, L; Fernandes, K; Aoubala, M; Quinlan, P; Purdie, C.A; Jordan, L.B; Prats, A; Lane, D.P ; Thompson, A.M
102014Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2Chee S.M.Q.; Wongsantichon J.; Soo Tng Q.; Robinson R. ; Joseph T.L.; Verma C. ; Lane D.P. ; Brown C.J.; Ghadessy F.J.