Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/97733
Title: Raman microspectroscopy of the brain tissues in the substantia nigra and MPTP-induced Parkinson's disease
Authors: Ong, C.W.
Shen, Z.X. 
He, Y.
Lee, T. 
Tang, S.H. 
Issue Date: 1999
Citation: Ong, C.W.,Shen, Z.X.,He, Y.,Lee, T.,Tang, S.H. (1999). Raman microspectroscopy of the brain tissues in the substantia nigra and MPTP-induced Parkinson's disease. Journal of Raman Spectroscopy 30 (2) : 91-96. ScholarBank@NUS Repository.
Abstract: The substantia nigra of the rostral mid-brain of a monkey was studied using Raman microspectroscopy. The white and grey matter could be clearly distinguished and their relative proportions evaluated from the Raman peaks in the 3000 cm-1 region. Raman spectra obtained from the substantia nigra for both treated and untreated samples showed that the process of staining the neuron nuclei affected the brain cells and the quality of the Raman spectra from the treated samples was poorer. The brain cells of a monkey suffering from Parkinson's disease was also studied. Raman spectra collected from the control cells and the diseased cells did not show a clear difference. Copyright © 1999 John Wiley & Sons, Ltd.
Source Title: Journal of Raman Spectroscopy
URI: http://scholarbank.nus.edu.sg/handle/10635/97733
ISSN: 03770486
Appears in Collections:Staff Publications

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