Please use this identifier to cite or link to this item: https://doi.org/10.1155/2012/294528
Title: Pilot study with regard to the wound healing activity of protein from calotropis procera (Ait.) R. Br.
Authors: Perumal Samy, R. 
Chow, V.T.K.
Issue Date: 2012
Citation: Perumal Samy, R., Chow, V.T.K. (2012). Pilot study with regard to the wound healing activity of protein from calotropis procera (Ait.) R. Br.. Evidence-based Complementary and Alternative Medicine 2012 : -. ScholarBank@NUS Repository. https://doi.org/10.1155/2012/294528
Abstract: We provide the scientific basis for the use of Calotropis procera for treating skin and wound infections in traditional medicine. The aqueous extract of stem-bark of C. procera exhibited more pronounced potent antimicrobial activity. Calo-protein was purified and identified from the most-active aqueous extracts of C. procera and showed broad-spectrum activity. Calo-protein inhibited the growth of S. aureus and E. aerogenes effectively at 25 μg/ml concentration. Mice topically treated with Calo-protein revealed significant wound healing after 14 days comparable to fusidic acid (FA) as positive control. This protein was devoid of cytolytic effect even at higher concentrations on skin cells after 24 h. Further investigation of this Calo-protein of C. procera on bacterial inhibition may provide a better understanding of the scientific basis and justification for its use in traditional medicine. © 2012 Ramar Perumal Samy and Vincent T. K. Chow.
Source Title: Evidence-based Complementary and Alternative Medicine
URI: http://scholarbank.nus.edu.sg/handle/10635/97550
ISSN: 1741427X
DOI: 10.1155/2012/294528
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

6
checked on Jul 11, 2018

Page view(s)

21
checked on Jun 29, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.