Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/95241
Title: The Michael Addition of Indole to α,β-Unsaturated Ketones Catalyzed by Iodine at Room Temperature
Authors: Wang, S.-Y.
Ji, S.-J.
Loh, T.-P. 
Keywords: Indoles
Michael reaction
Molecular iodine
Issue Date: 2003
Citation: Wang, S.-Y.,Ji, S.-J.,Loh, T.-P. (2003). The Michael Addition of Indole to α,β-Unsaturated Ketones Catalyzed by Iodine at Room Temperature. Synlett (15) : 2377-2379. ScholarBank@NUS Repository.
Abstract: Indole undergoes conjugate addition with α,β-unsaturated ketones by means of alkylation of indole in the presence of a catalytic amount of molecular I2 at room temperature to afford the corresponding adduct in excellent yields (up to 96%). The substitution on the indole nucleus occurred exclusively at the 3-position. N-alkylation products have not been observed.
Source Title: Synlett
URI: http://scholarbank.nus.edu.sg/handle/10635/95241
ISSN: 09365214
Appears in Collections:Staff Publications

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