Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tetlet.2004.10.146
Title: Synthetic studies towards anti-SARS agents: Application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate
Authors: Chng, S.-S.
Hoang, T.-G.
Wayne Lee, W.-W.
Tham, M.-P.
Ling, H.Y.
Loh, T.-P. 
Keywords: AG7088
Anti-SARS agents
Diastereoselective
Indium-mediated allylation
Issue Date: 20-Dec-2004
Source: Chng, S.-S., Hoang, T.-G., Wayne Lee, W.-W., Tham, M.-P., Ling, H.Y., Loh, T.-P. (2004-12-20). Synthetic studies towards anti-SARS agents: Application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate. Tetrahedron Letters 45 (52) : 9501-9504. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2004.10.146
Abstract: AG7088 was identified as a good starting point for modification, leading to an efficient and bio-available inhibitor for the SARS coronavirus main proteinase (SARS-CoV M pro). Synthesis of intermediate 1 and analogues proceeded via a highly diastereoselective indium-mediated allylation of α-aminoaldehydes. © 2004 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/95185
ISSN: 00404039
DOI: 10.1016/j.tetlet.2004.10.146
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