Please use this identifier to cite or link to this item: https://doi.org/10.1021/la102556u
Title: Nanocomposites containing gold nanorods and porphyrin-doped mesoporous silica with dual capability of two-photon imaging and photosensitization
Authors: Zhao, T.
Wu, H. 
Yao, S.Q. 
Xu, Q.-H. 
Xu, G.Q. 
Issue Date: 21-Sep-2010
Citation: Zhao, T., Wu, H., Yao, S.Q., Xu, Q.-H., Xu, G.Q. (2010-09-21). Nanocomposites containing gold nanorods and porphyrin-doped mesoporous silica with dual capability of two-photon imaging and photosensitization. Langmuir 26 (18) : 14937-14942. ScholarBank@NUS Repository. https://doi.org/10.1021/la102556u
Abstract: Novel multifunctional nanoparticles that combine two functionalities (a gold nanorod core and a porphyrin-doped mesoporous silica shell) into one entity were synthesized. Due to the encapsulation of mesoporous silica, the porphyrin can be well protected against the external bioenvironment. In addition, the generated singlet oxygen by porphyrin molecules can be easily released from the silica. We have demonstrated that these multifunctional nanoparticles can generate singlet oxygen with relatively higher yield compared to free porphyrin. These multifunctional nanocomposites are attractive candidates for simultaneous photosensitization and two-photon imaging as well as imaging guided therapy. © 2010 American Chemical Society.
Source Title: Langmuir
URI: http://scholarbank.nus.edu.sg/handle/10635/94344
ISSN: 07437463
DOI: 10.1021/la102556u
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