Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/94281
Title: Mitochondrial affinity of guanidine-rich molecular transporters built on mγo- and scγllo-inositol scaffolds: Stereochemistry dependency
Authors: Ghosh, S.C.
Kim, B.
Im, J.
Lee, W.S.
Im, C.-N. 
Chang, Y.-T. 
Kim, W.
Kim, K.-T.
Chung, S.-K.
Keywords: Blood-brain barrier
Cellular membrane
Drug delivery
Inositol scaffold
Mitochondrial affinity
Issue Date: 20-Dec-2010
Citation: Ghosh, S.C., Kim, B., Im, J., Lee, W.S., Im, C.-N., Chang, Y.-T., Kim, W., Kim, K.-T., Chung, S.-K. (2010-12-20). Mitochondrial affinity of guanidine-rich molecular transporters built on mγo- and scγllo-inositol scaffolds: Stereochemistry dependency. Bulletin of the Korean Chemical Society 31 (12) : 3623-3631. ScholarBank@NUS Repository.
Abstract: We prepared several novel molecular transporters built on myo- and scylloinositol scaffolds with variations in the number of guanidine residues, linker chain lengths and patterns. Some of these transporters were found to localize in mitochondria, and the mitochondrial affinity seems to be substantially related to the scaffold stereochemistry.
Source Title: Bulletin of the Korean Chemical Society
URI: http://scholarbank.nus.edu.sg/handle/10635/94281
ISSN: 02532964
Appears in Collections:Staff Publications

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