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|Title:||In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities|
|Citation:||Cheng, X., Li, L., Uttamchandani, M., Yao, S.Q. (2014-03-07). In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities. Organic Letters 16 (5) : 1414-1417. ScholarBank@NUS Repository. https://doi.org/10.1021/ol500206w|
|Abstract:||A library of cell-permeable, minimally tagged C75 analogues was synthesized and used to uncover biological targets in human liver cancer cells. Known targets of C75, namely FASN and CPT1A, together with other unknown targets, including PDIA3, TFRC, and GAPDH, were thus identified. © 2014 American Chemical Society.|
|Source Title:||Organic Letters|
|Appears in Collections:||Staff Publications|
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