Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0021-9673(02)01191-3
Title: Determination of five toxic alkaloids in two common herbal medicines with capillary electrophoresis
Authors: Feng, H.-T.
Li, S.F.Y. 
Keywords: Aconitine
Alkaloids
Brucine
Herbal medicines
Hypaconitine
Mesaconitine
Strychnine
Issue Date: 11-Oct-2002
Citation: Feng, H.-T., Li, S.F.Y. (2002-10-11). Determination of five toxic alkaloids in two common herbal medicines with capillary electrophoresis. Journal of Chromatography A 973 (1-2) : 243-247. ScholarBank@NUS Repository. https://doi.org/10.1016/S0021-9673(02)01191-3
Abstract: A method was developed for the determination of five highly toxic alkaloids in two commonly used herbal medicines by capillary electrophoresis, which had not been applied to the determination of Aconitum alkaloids before. The buffer contained 40 mM ammonium acetate and 0.1% acetic acid in 80% methanol. Five alkaloids can be determined in 15 min by a single run. The calibration curves showed a linear range from 2 to 200 mg/l for these alkaloids with correlation coefficients (R2) between 0.9988 and 0.9999. Detection limits (S/N=3) varied from 0.85 to 1.90 mg/l. Recoveries ranged from 95 to 108.8%. The method can provide an effective tool for the strict control of these fetal herbal medicine components. © 2002 Elsevier Science B.V. All rights reserved.
Source Title: Journal of Chromatography A
URI: http://scholarbank.nus.edu.sg/handle/10635/93549
ISSN: 00219673
DOI: 10.1016/S0021-9673(02)01191-3
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