Please use this identifier to cite or link to this item:
|Title:||Determination of degradation products of chemical warfare agents in water using hollow fibre-protected liquid-phase microextraction with in-situ derivatisation followed by gas chromatography-mass spectrometry|
|Keywords:||Chemical warfare agent degradation products|
Gas chromatography-mass spectrometry
|Citation:||Lee, H.S.N., Sng, M.T., Basheer, C., Lee, H.K. (2007-04-27). Determination of degradation products of chemical warfare agents in water using hollow fibre-protected liquid-phase microextraction with in-situ derivatisation followed by gas chromatography-mass spectrometry. Journal of Chromatography A 1148 (1) : 8-15. ScholarBank@NUS Repository. https://doi.org/10.1016/j.chroma.2007.02.104|
|Abstract:||Hollow fibre-protected liquid-phase microextraction (HF-LPME) together with gas chromatography/mass spectrometry was investigated for the analysis of degradation products of chemical warfare agents in water samples. The degradation products studied were those of nerve and blister agents, and a psychotomimetic agent. Extractions were successfully performed coupled with in-situ derivatisation using a mixture of solvent and derivatising agent. The protection of the moisture-sensitive derivatising agent was afforded by the hollow fibre. Parameters such as extraction solvent, pH, salt concentration, stirring speed and extraction time were optimised using spiked deionised water samples. The linear range established was between 0.005 and 5 μg ml-1 depending on analyte, with squared regression coefficients ranging from 0.9929 to 1.0000. Relative standard deviations ranged from 9% to 22%. As compared to those of solid-phase microextraction, the limits of detection (0.01-0.54 μg l-1) of the newly-developed approach were significantly improved. © 2007 Elsevier B.V. All rights reserved.|
|Source Title:||Journal of Chromatography A|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 13, 2018
WEB OF SCIENCETM
checked on Jun 18, 2018
checked on Jun 29, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.