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https://doi.org/10.1016/S0040-4039(02)00998-X
Title: | The first Bischler-Napieralski cyclization in a room temperature ionic liquid | Authors: | Judeh, Z.M.A. Ching, C.B. Bu, J. McCluskey, A. |
Keywords: | Bischler-Napieralski cyclization Ionic liquids Isoquinolines |
Issue Date: | 15-Jul-2002 | Citation: | Judeh, Z.M.A., Ching, C.B., Bu, J., McCluskey, A. (2002-07-15). The first Bischler-Napieralski cyclization in a room temperature ionic liquid. Tetrahedron Letters 43 (29) : 5089-5091. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(02)00998-X | Abstract: | We have demonstrated the use of the room temperature ionic liquid, 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF6), as an environmentally benign solvent for the preparation of isoquinoline derivatives through Bischler-Napieralski cyclization under mild conditions with excellent purity and yields. The role of HF as a catalyst in the reaction was also investigated. © 2002 Elsevier Science Ltd. All rights reserved. | Source Title: | Tetrahedron Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/92421 | ISSN: | 00404039 | DOI: | 10.1016/S0040-4039(02)00998-X |
Appears in Collections: | Staff Publications |
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