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|Title:||The first Bischler-Napieralski cyclization in a room temperature ionic liquid|
|Citation:||Judeh, Z.M.A., Ching, C.B., Bu, J., McCluskey, A. (2002-07-15). The first Bischler-Napieralski cyclization in a room temperature ionic liquid. Tetrahedron Letters 43 (29) : 5089-5091. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(02)00998-X|
|Abstract:||We have demonstrated the use of the room temperature ionic liquid, 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF6), as an environmentally benign solvent for the preparation of isoquinoline derivatives through Bischler-Napieralski cyclization under mild conditions with excellent purity and yields. The role of HF as a catalyst in the reaction was also investigated. © 2002 Elsevier Science Ltd. All rights reserved.|
|Source Title:||Tetrahedron Letters|
|Appears in Collections:||Staff Publications|
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