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Title: Concentration control for semi-batch ph-shift reactive crystallization of L-glutamic acid
Authors: Su, Q.L.
Braatz, R.D.
Chiu, M.-S. 
Issue Date: 2012
Citation: Su, Q.L.,Braatz, R.D.,Chiu, M.-S. (2012). Concentration control for semi-batch ph-shift reactive crystallization of L-glutamic acid. IFAC Proceedings Volumes (IFAC-PapersOnline) 8 (PART 1) : 228-233. ScholarBank@NUS Repository.
Abstract: While major advances have been made in the control of cooling and antisolvent crystallizations, very little progress has been made for the much more challenging pH-shift reactive crystallizations that are also quite common in industry. This paper extends the concentration control strategy developed for cooling and antisolvent crystallization to pH-shift reactive crystallization of L-glutamic acid. The straightforward extension to semi-batch pH-shift reactive crystallization is not applicable, which motivates a variant that incorporates data-based models so as to better cope with process nonlinearity. Further analysis motivates the development of control strategies that directly incorporate measurements of the key product quality attributes. © 2012 IFAC.
Source Title: IFAC Proceedings Volumes (IFAC-PapersOnline)
ISBN: 9783902823052
ISSN: 14746670
DOI: 10.3182/20120710-4-SG-2026.00131
Appears in Collections:Staff Publications

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