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|Title:||Concentration control for semi-batch ph-shift reactive crystallization of L-glutamic acid|
|Citation:||Su, Q.L.,Braatz, R.D.,Chiu, M.-S. (2012). Concentration control for semi-batch ph-shift reactive crystallization of L-glutamic acid. IFAC Proceedings Volumes (IFAC-PapersOnline) 8 (PART 1) : 228-233. ScholarBank@NUS Repository. https://doi.org/10.3182/20120710-4-SG-2026.00131|
|Abstract:||While major advances have been made in the control of cooling and antisolvent crystallizations, very little progress has been made for the much more challenging pH-shift reactive crystallizations that are also quite common in industry. This paper extends the concentration control strategy developed for cooling and antisolvent crystallization to pH-shift reactive crystallization of L-glutamic acid. The straightforward extension to semi-batch pH-shift reactive crystallization is not applicable, which motivates a variant that incorporates data-based models so as to better cope with process nonlinearity. Further analysis motivates the development of control strategies that directly incorporate measurements of the key product quality attributes. © 2012 IFAC.|
|Source Title:||IFAC Proceedings Volumes (IFAC-PapersOnline)|
|Appears in Collections:||Staff Publications|
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