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Title: Modified reactive SMB for production of high concentrated fructose syrup by isomerization of glucose to fructose
Authors: Zhang, Y.
Hidajat, K. 
Ray, A.K.
Keywords: Bioprocess design
Moving bed bioreactor
Issue Date: 1-Aug-2007
Citation: Zhang, Y., Hidajat, K., Ray, A.K. (2007-08-01). Modified reactive SMB for production of high concentrated fructose syrup by isomerization of glucose to fructose. Biochemical Engineering Journal 35 (3) : 341-351. ScholarBank@NUS Repository.
Abstract: This work presents modifications to the Hashimoto's hybrid simulated moving bed reactor (SMBR) system which was used to produce 55% high fructose syrup (HFS55). The purpose of this study is to develop a new SMBR system to overcome the disadvantages of Hashimoto system (3-zone SMB with seven reactors), i.e., low utility of reactors when feed being a 50/50 blend of glucose and fructose. Two different configurations of modified system were presented in this paper: the first configuration is 4-zone SMB with one reactor, while the other one consists of one additional reactor. Both of these configurations aim at improving the concentration and purity of glucose at the inlet of the reactor, which will lead to both high productivity and high purity of fructose in the product. A state-of-the-art optimization technique, viz., non-dominated sorting genetic algorithm (NSGA) is used in finding the optimal design and operating parameters for the modified reactive SMB and Varicol processes. Compared with the Hashimoto's system, high productivity and purity of fructose can be achieved in these new systems using less number of reactors. © 2007 Elsevier B.V. All rights reserved.
Source Title: Biochemical Engineering Journal
ISSN: 1369703X
DOI: 10.1016/j.bej.2007.01.026
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