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|Title:||Highly efficient production of l-lactic acid from xylose by newly isolated Bacillus coagulans C106|
|Citation:||Ye, L., Zhou, X., Hudari, M.S.B., Li, Z., Wu, J.C. (2013-03). Highly efficient production of l-lactic acid from xylose by newly isolated Bacillus coagulans C106. Bioresource Technology 132 : 38-44. ScholarBank@NUS Repository. https://doi.org/10.1016/j.biortech.2013.01.011|
|Abstract:||Cost-effective production of optically pure lactic acid from lignocellulose sugars is commercially attractive but challenging. Bacillus coagulans C106 was isolated from environment and used to produce l-lactic acid from xylose at 50°C and pH 6.0 in mineral salts medium containing 1-2% (w/v) of yeast extract without sterilizing the medium before fermentation. In batch fermentation with 85g/L of xylose, lactic acid titer and productivity reached 83.6g/L and 7.5g/Lh, respectively. When fed-batch (120+80+60g/L) fermentation was applied, they reached 215.7g/L and 4.0g/Lh, respectively. In both cases, the lactic acid yield and optical purity reached 95% and 99.6%, respectively. The lactic acid titer and productivity on xylose are the highest among those ever reported. Ca(OH)2 was found to be a better neutralizing agent than NaOH in terms of its giving higher lactic acid titer (1.2-fold) and productivity (1.8-fold) under the same conditions. © 2013 Elsevier Ltd.|
|Source Title:||Bioresource Technology|
|Appears in Collections:||Staff Publications|
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