Please use this identifier to cite or link to this item:
|Title:||A novel dual-layer forward osmosis membrane for protein enrichment and concentration|
|Authors:||Yang, Q. |
Dual-layer hollow fiber membrane
|Citation:||Yang, Q., Wang, K.Y., Chung, T.-S. (2009-10-15). A novel dual-layer forward osmosis membrane for protein enrichment and concentration. Separation and Purification Technology 69 (3) : 269-274. ScholarBank@NUS Repository. https://doi.org/10.1016/j.seppur.2009.08.002|
|Abstract:||We have demonstrated the prospect of dual-layer polybenzimidazole-polyethersulfone/polyvinylpyrrolidone (PBI-PES/PVP) hollow fiber nanofiltration (NF) membranes in the forward osmosis (FO) process for the enrichment and concentration of pharmaceutical products without denaturing the component of interests. The dual-layer hollow fiber membrane via coextrusion technology has an ultra-thin selective skin around 10 μm, fully open-cell water channels underneath and a microporous sponge-like support structure. The self-charged PBI selective skin has an average pore radius at 0.4 nm with a sharp pore size distribution. Experimental results show that the newly developed dual-layer hollow fiber nanofiltration membrane can achieve a high throughput for lysozyme enrichment and less protein fouling when using it as a FO membrane. In addition, the high divalent salt rejection towards Mg2+ at around 90% of this dual-layer membrane ensures the enriched lysozyme product with high purity and without change and denaturing. © 2009 Elsevier B.V. All rights reserved.|
|Source Title:||Separation and Purification Technology|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Oct 18, 2018
WEB OF SCIENCETM
checked on Oct 10, 2018
checked on Oct 5, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.