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Title: Optical imaging-guided cancer therapy with fluorescent nanoparticles
Authors: Jiang, S.
Gnanasammandhan, M.K.
Zhang, Y. 
Keywords: Cancer therapy
Fluorescent nanoparticles
Optical imaging
Issue Date: 1-Jun-2009
Citation: Jiang, S., Gnanasammandhan, M.K., Zhang, Y. (2009-06-01). Optical imaging-guided cancer therapy with fluorescent nanoparticles. Journal of the Royal Society Interface 7 (42) : 3-18. ScholarBank@NUS Repository.
Abstract: The diagnosis and treatment of cancer have been greatly improved with the recent developments in nanotechnology. One of the promising nanoscale tools for cancer diagnosis is fluorescent nanoparticles (NPs), such as organic dye-doped NPs, quantum dots and upconversion NPs that enable highly sensitive optical imaging of cancer at cellular and animal level. Furthermore, the emerging development of novel multi-functional NPs, which can be conjugated with several functional molecules simultaneously including targeting moieties, therapeutic agents and imaging probes, provides new potentials for clinical therapies and diagnostics and undoubtedly will play a critical role in cancer therapy. In this article, we review the types and characteristics of fluorescent NPs, in vitro and in vivo imaging of cancer using fluorescent NPs and multi-functional NPs for imaging-guided cancer therapy. © 2009 The Royal Society.
Source Title: Journal of the Royal Society Interface
ISSN: 17425689
DOI: 10.1098/rsif.2009.0243
Appears in Collections:Staff Publications

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