Please use this identifier to cite or link to this item: https://doi.org/10.1557/opl.2011.1172
Title: Simultaneous gene delivery and tracking of cells using fluorescent upconversion nanoparticles for cell therapy
Authors: Jayakumar, M.K.G.
Zhang, Y. 
Issue Date: 2011
Source: Jayakumar, M.K.G.,Zhang, Y. (2011). Simultaneous gene delivery and tracking of cells using fluorescent upconversion nanoparticles for cell therapy. Materials Research Society Symposium Proceedings 1355 : 34-37. ScholarBank@NUS Repository. https://doi.org/10.1557/opl.2011.1172
Abstract: Cell therapy has attained new heights with the current developments in the field of stem cell therapy and is often done in combination with gene therapy. Much research has gone into developing safe vectors to deliver genes to the cells used for cell therapy and also in tracking the transplanted cells and determining their fate. Even though viral vectors are very efficient in gene delivery, there are major safety concerns related to it. Herein, we report the use of novel fluorescent upconversion nanoparticles (UCNs) for simultaneous gene delivery and tracking of cells for cell-based therapies. It is a safe alternative to viral vectors and offers imaging capabilities too, which will give an insight on the fate of transplanted cells. © 2011 Materials Research Society.
Source Title: Materials Research Society Symposium Proceedings
URI: http://scholarbank.nus.edu.sg/handle/10635/88352
ISBN: 9781627482004
ISSN: 02729172
DOI: 10.1557/opl.2011.1172
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

50
checked on Jan 19, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.