Please use this identifier to cite or link to this item:
|Title:||Using 3D fluid-structure interaction model to analyse the biomechanical properties of erythrocyte|
Computational fluid-structure interaction
|Source:||Chee, C.Y., Lee, H.P., Lu, C. (2008-02-25). Using 3D fluid-structure interaction model to analyse the biomechanical properties of erythrocyte. Physics Letters, Section A: General, Atomic and Solid State Physics 372 (9) : 1357-1362. ScholarBank@NUS Repository. https://doi.org/10.1016/j.physleta.2007.09.067|
|Abstract:||This Letter presents a newly developed three-dimensional fluid-structure interaction model of the red blood cell (RBC). The model consists of a deformable liquid capsule modelled as Newtonian fluid enclosed by a hyperelastic membrane with viscoelastic property. Numerical results show that viscosity in the cytoplasm affects the deformed shape of RBC under loading. This observation is contrary to the earlier belief that viscosity of the cytoplasm can be neglected. Numerical simulations carried out to investigate large deformation induced on the RBC model using direct tensile forces show significant improvement in terms of correlation with experimental results. The membrane shear modulus estimated from the model ranges between 3.7 to 9.0 μN m-1 compares well with results obtained from micropipette aspiration experiments. © 2007 Elsevier B.V. All rights reserved.|
|Source Title:||Physics Letters, Section A: General, Atomic and Solid State Physics|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 15, 2018
WEB OF SCIENCETM
checked on Jan 31, 2018
checked on Feb 19, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.