Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.actbio.2009.08.012
Title: The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts
Authors: Thian, E.S. 
Ahmad, Z.
Huang, J.
Edirisinghe, M.J.
Jayasinghe, S.N.
Ireland, D.C.
Brooks, R.A.
Rushton, N.
Bonfield, W.
Best, S.M.
Keywords: Carbonate
Electrospraying
Nanoapatites
Osteoblasts
Silicon
Issue Date: Mar-2010
Citation: Thian, E.S., Ahmad, Z., Huang, J., Edirisinghe, M.J., Jayasinghe, S.N., Ireland, D.C., Brooks, R.A., Rushton, N., Bonfield, W., Best, S.M. (2010-03). The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts. Acta Biomaterialia 6 (3) : 750-755. ScholarBank@NUS Repository. https://doi.org/10.1016/j.actbio.2009.08.012
Abstract: A new deposition method is presented, based on electrospraying, that can build bioceramic structures with desirable surface properties. This technology allows nanoapatite crystals, including hydroxyapatite (nHA), carbonate-substituted HA (nCHA) and silicon-substituted HA (nSiHA), to be electrosprayed on glass substrates. Human osteoblast cells cultured on nSiHA showed enhanced cell attachment, proliferation and protein expression, namely alkaline phosphatase, type 1 collagen and osteocalcin, as compared to nHA and nCHA. The modification of nanoapatite by the addition of silicon into the HA lattice structure renders the electrosprayed surface more hydrophilic and electronegatively charged. © 2009 Acta Materialia Inc.
Source Title: Acta Biomaterialia
URI: http://scholarbank.nus.edu.sg/handle/10635/85780
ISSN: 17427061
DOI: 10.1016/j.actbio.2009.08.012
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