Please use this identifier to cite or link to this item: https://doi.org/10.1002/1522-2683(200109)22:17<3683
Title: Spatial temperature gradient capillary electrophoresis for DNA mutation detection
Authors: Zhu, L. 
Lee, H.K. 
Lin, B.
Yeung, E.S.
Keywords: DNA mutation
Spatial temperature gradient capillary electrophoresis
Issue Date: 2001
Source: Zhu, L.,Lee, H.K.,Lin, B.,Yeung, E.S. (2001). Spatial temperature gradient capillary electrophoresis for DNA mutation detection. Electrophoresis 22 (17) : 3683-3687. ScholarBank@NUS Repository. https://doi.org/10.1002/1522-2683(200109)22:17<3683
Abstract: A continuous spatial temperature gradient was established in capillary electrophoresis by using a simple temperature control device. The temperature profile along the capillary was predicted by theoretical calculations. A nearly linear spatial temperature gradient was established and applied to DNA mutation detection. By spanning a wide temperature range, it was possible to perform simultaneous heteroduplex analysis for various mutation types that have different melting temperatures.
Source Title: Electrophoresis
URI: http://scholarbank.nus.edu.sg/handle/10635/77032
ISSN: 01730835
DOI: 10.1002/1522-2683(200109)22:17<3683
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