Please use this identifier to cite or link to this item:
|Title:||Molecular recognition in a palladium complex promoted asymmetric synthesis of a P-chiral heterodifunctionalized bidentate phosphine ligand|
|Source:||Song, Y.,Vittal, J.J.,Chan, S.-H.,Leung, P.-H. (1999-02-15). Molecular recognition in a palladium complex promoted asymmetric synthesis of a P-chiral heterodifunctionalized bidentate phosphine ligand. Organometallics 18 (4) : 650-655. ScholarBank@NUS Repository.|
|Abstract:||The organopalladium complex containing orthometalated (S)-(1-(dimethylamino)ethyl)-naphthalene as the chiral auxiliary has been used successfully to promote the asymmetric [4+2] Diels-Alder reaction between 3,4-dimethyl-1-phenylphosphole and 2-methylene-3-quinuclidinone. In this reaction, the organopalladium template exhibited remarkable stereochemical and electronic directing effects such that the quinuclidinone-nitrogen atom in the resulting phosphanorbornene cycloadduct is located stereospecifically in the exo position. Only one enantiomerically pure P-N bidentate ligand was obtained, although four diastereomeric products are possible. The absolute configuration and the coordination properties of the P-chiral cycloadduct have been established by single-crystal X-ray analyses.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 13, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.