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https://doi.org/10.5012/bkcs.2010.31.12.3623
| Title: | Mitochondrial affinity of guanidine-rich molecular transporters built on mγo- and scγllo-inositol scaffolds: Stereochemistry dependency | Authors: | Ghosh, S.C. Kim, B. Im, J. Lee, W.S. Im, C.-N. Chang, Y.-T. Kim, W. Kim, K.-T. Chung, S.-K. |
Keywords: | Blood-brain barrier Cellular membrane Drug delivery Inositol scaffold Mitochondrial affinity |
Issue Date: | 20-Dec-2010 | Citation: | Ghosh, S.C., Kim, B., Im, J., Lee, W.S., Im, C.-N., Chang, Y.-T., Kim, W., Kim, K.-T., Chung, S.-K. (2010-12-20). Mitochondrial affinity of guanidine-rich molecular transporters built on mγo- and scγllo-inositol scaffolds: Stereochemistry dependency. Bulletin of the Korean Chemical Society 31 (12) : 3623-3631. ScholarBank@NUS Repository. https://doi.org/10.5012/bkcs.2010.31.12.3623 | Abstract: | We prepared several novel molecular transporters built on myo- and scylloinositol scaffolds with variations in the number of guanidine residues, linker chain lengths and patterns. Some of these transporters were found to localize in mitochondria, and the mitochondrial affinity seems to be substantially related to the scaffold stereochemistry. | Source Title: | Bulletin of the Korean Chemical Society | URI: | http://scholarbank.nus.edu.sg/handle/10635/76575 | ISSN: | 02532964 | DOI: | 10.5012/bkcs.2010.31.12.3623 |
| Appears in Collections: | Staff Publications |
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