L-Threonine-derived novel bifunctional phosphine-sulfonamide catalyst-promoted enantioselective aza-morita-Baylis-Hillman reaction

Please use this identifier to cite or link to this item: https://doi.org/10.1021/ol103145g

Title:	L-Threonine-derived novel bifunctional phosphine-sulfonamide catalyst-promoted enantioselective aza-morita-Baylis-Hillman reaction
Authors:	Zhong, F. Wang, Y. Han, X. Huang, K.-W. Lu, Y.
Issue Date:	18-Mar-2011
Citation:	Zhong, F., Wang, Y., Han, X., Huang, K.-W., Lu, Y. (2011-03-18). L-Threonine-derived novel bifunctional phosphine-sulfonamide catalyst-promoted enantioselective aza-morita-Baylis-Hillman reaction. Organic Letters 13 (6) : 1310-1313. ScholarBank@NUS Repository. https://doi.org/10.1021/ol103145g
Abstract:	A series of novel bifunctional phosphine-sulfonamide organic catalysts were designed and readily prepared from natural amino acids, and they were utilized to promote enantioselective aza-Morita-Baylis-Hillman (MBH) reactions. l-Threonine-derived phosphine-sulfonamide 9b was found to be the most efficient catalyst, affording the desired aza-MBH adducts in high yields and with excellent enantioselectivities. © 2011 American Chemical Society.
Source Title:	Organic Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/76460
ISSN:	15237060
DOI:	10.1021/ol103145g
Appears in Collections:	Staff Publications

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