Please use this identifier to cite or link to this item: https://doi.org/10.1039/c3ob41267a
Title: Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles
Authors: Dou, X.
Lu, Y. 
Issue Date: 28-Aug-2013
Citation: Dou, X., Lu, Y. (2013-08-28). Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles. Organic and Biomolecular Chemistry 11 (32) : 5217-5221. ScholarBank@NUS Repository. https://doi.org/10.1039/c3ob41267a
Abstract: An organocatalytic conjugate addition of prochiral 3-fluorinated oxindoles to vinyl sulfones was described for the first time. In the presence of bifunctional tertiary amine-thiourea catalysts, 3-fluoro-3-substituted oxindole adducts were obtained in excellent yields and with high enantiomeric excesses.© 2013 The Royal Society of Chemistry.
Source Title: Organic and Biomolecular Chemistry
URI: http://scholarbank.nus.edu.sg/handle/10635/76097
ISSN: 14770520
DOI: 10.1039/c3ob41267a
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