Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles

Please use this identifier to cite or link to this item: https://doi.org/10.1039/c3ob41267a

Title:	Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles
Authors:	Dou, X. Lu, Y.
Issue Date:	28-Aug-2013
Citation:	Dou, X., Lu, Y. (2013-08-28). Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles. Organic and Biomolecular Chemistry 11 (32) : 5217-5221. ScholarBank@NUS Repository. https://doi.org/10.1039/c3ob41267a
Abstract:	An organocatalytic conjugate addition of prochiral 3-fluorinated oxindoles to vinyl sulfones was described for the first time. In the presence of bifunctional tertiary amine-thiourea catalysts, 3-fluoro-3-substituted oxindole adducts were obtained in excellent yields and with high enantiomeric excesses.© 2013 The Royal Society of Chemistry.
Source Title:	Organic and Biomolecular Chemistry
URI:	http://scholarbank.nus.edu.sg/handle/10635/76097
ISSN:	14770520
DOI:	10.1039/c3ob41267a
Appears in Collections:	Staff Publications

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