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|Title:||Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles|
|Citation:||Dou, X., Lu, Y. (2013-08-28). Enantioselective conjugate addition of 3-fluoro-oxindoles to vinyl sulfone: An organocatalytic access to chiral 3-fluoro-3-substituted oxindoles. Organic and Biomolecular Chemistry 11 (32) : 5217-5221. ScholarBank@NUS Repository. https://doi.org/10.1039/c3ob41267a|
|Abstract:||An organocatalytic conjugate addition of prochiral 3-fluorinated oxindoles to vinyl sulfones was described for the first time. In the presence of bifunctional tertiary amine-thiourea catalysts, 3-fluoro-3-substituted oxindole adducts were obtained in excellent yields and with high enantiomeric excesses.© 2013 The Royal Society of Chemistry.|
|Source Title:||Organic and Biomolecular Chemistry|
|Appears in Collections:||Staff Publications|
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