Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity

Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2cc35070j

Title:	Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity
Authors:	Shen, W. Deng, H. Teo, A.K.L. Gao, Z.
Issue Date:	21-Oct-2012
Citation:	Shen, W., Deng, H., Teo, A.K.L., Gao, Z. (2012-10-21). Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity. Chemical Communications 48 (82) : 10225-10227. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc35070j
Abstract:	Coupling gold nanoparticle-based ligation to a ligation chain reaction enables colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity. One mutant in 2000 copies of a wild-type gene can be detected in 20-100 pg of PCR-amplified genomic DNA samples. © The Royal Society of Chemistry 2012.
Source Title:	Chemical Communications
URI:	http://scholarbank.nus.edu.sg/handle/10635/75768
ISSN:	13597345
DOI:	10.1039/c2cc35070j
Appears in Collections:	Staff Publications

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