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|Title:||Click-based synthesis and proteomic profiling of lipstatin analogues|
|Authors:||Ngai, M.H. |
|Citation:||Ngai, M.H., Yang, P.-Y., Liu, K., Shen, Y., Wenk, M.R., Yao, S.Q., Lear, M.J. (2010-11-28). Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications 46 (44) : 8335-8337. ScholarBank@NUS Repository. https://doi.org/10.1039/c0cc01276a|
|Abstract:||Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved ability to induce tumour cell death. © 2010 The Royal Society of Chemistry.|
|Source Title:||Chemical Communications|
|Appears in Collections:||Staff Publications|
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