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|Title:||Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: Asymmetric preparation of 3-nitro-1,2-dihydroquinolines|
|Citation:||Liu, X., Lu, Y. (2010-09-21). Bifunctional thiourea-promoted cascade aza-Michael-Henry-dehydration reactions: Asymmetric preparation of 3-nitro-1,2-dihydroquinolines. Organic and Biomolecular Chemistry 8 (18) : 4063-4065. ScholarBank@NUS Repository. https://doi.org/10.1039/c0ob00223b|
|Abstract:||A cascade aza-Michael-Henry-dehydration reaction catalyzed by quinidine-derived tertiary amine-thiourea catalyst was developed via installation of suitable electron withdrawing groups at the amino function of aniline. This strategy led to a one-step preparation of chiral 3-nitro-1,2-dihydroquinolines in high yields and with up to 90% enantiomeric excesses. © 2010 The Royal Society of Chemistry.|
|Source Title:||Organic and Biomolecular Chemistry|
|Appears in Collections:||Staff Publications|
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