A divergent approach to apoptolidin and FD-891: Asymmetric preparation of a common intermediate

Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0040-4039(03)01173-0

Title:	A divergent approach to apoptolidin and FD-891: Asymmetric preparation of a common intermediate
Authors:	Chng, S.-S. Xu, J. Loh, T.-P.
Keywords:	Apoptolidin Divergent synthesis FD-891
Issue Date:	30-Jun-2003
Citation:	Chng, S.-S., Xu, J., Loh, T.-P. (2003-06-30). A divergent approach to apoptolidin and FD-891: Asymmetric preparation of a common intermediate. Tetrahedron Letters 44 (27) : 4997-5000. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(03)01173-0
Abstract:	Biologically active Apoptolidin and FD-891 have structural similarity in their macrocyclic cores. Asymmetric preparation of a common intermediate in the total synthesis of these two macrolides is presented. A modified Masuyama Sn-allylation was employed to control the relative stereochemistry in the synthesis of the intermediate. © 2003 Elsevier Science Ltd. All rights reserved.
Source Title:	Tetrahedron Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/75408
ISSN:	00404039
DOI:	10.1016/S0040-4039(03)01173-0
Appears in Collections:	Staff Publications

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