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Title: Raman spectroscopy for optical diagnosis of laryngeal cancer
Authors: Teh, S.K. 
Zheng, W. 
Lau, D.P.
Huang, Z. 
Keywords: Cancer
Near-infrared Raman spectroscopy
Optical diagnosis
Issue Date: 2008
Source: Teh, S.K., Zheng, W., Lau, D.P., Huang, Z. (2008). Raman spectroscopy for optical diagnosis of laryngeal cancer. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6842 : -. ScholarBank@NUS Repository.
Abstract: In this report, the diagnostic ability of near-infrared (NIR) Raman spectroscopy for identifying the malignant tumors from normal tissues in the larynx was studied. A rapid NIR Raman system was utilized. Multivariate statistical techniques were employed to develop effective diagnostic algorithms. Raman spectra in the range of 800-1,800 cm-1 differed significantly between normal and malignant tumor tissues. The diagnostic algorithms can yielded a diagnostic sensitivity of 92.9% and specificity 83.3% for separating malignant tumors from normal laryngeal tissues. NIR Raman spectroscopy with multivariate statistical techniques has a potential for the non-invasive detection of malignant tumors in the larynx.
Source Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
ISBN: 9780819470171
ISSN: 16057422
DOI: 10.1117/12.761432
Appears in Collections:Staff Publications

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