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|Title:||Moving Raman spectroscopy into real-time, online diagnosis and detection of precancer and cancer in vivo in the upper GI during clinical endoscopic examination|
|Authors:||Huang, Z. |
in vivo diagnosis
near-infrared Raman spectroscopy
|Citation:||Huang, Z., Bergholt, M.S., Zheng, W., Ho, K.Y., Yeoh, K.G., Teh, M., So, J.B.Y., Shabbir, A. (2013). Moving Raman spectroscopy into real-time, online diagnosis and detection of precancer and cancer in vivo in the upper GI during clinical endoscopic examination. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 8577 : -. ScholarBank@NUS Repository. https://doi.org/10.1117/12.2005697|
|Abstract:||A rapid image-guided Raman endoscopy system integrated with on-line diagnostic scheme is developed for in vivo Raman tissue diagnosis (optical biopsy) in the upper GI during clinical gastrointestinal endoscopy under multimodal wide-field imaging guidance. The real-time Raman endoscopy technique was tested prospectively on new gastric patients (n=4) and could identify dysplasia in vivo with sensitivity of 81.5% (22/27) and specificity of 87.9% (29/33). This study realizes for the first time the novel image-guided Raman endoscopy as a screening tool for real-time, online diagnosis of gastric cancer and precancer in vivo at endoscopy. © 2013 Copyright SPIE.|
|Source Title:||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Appears in Collections:||Staff Publications|
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